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Compared to conventional CABG, randomised controlled trials (RCTs) have shown that off-pump coronary artery bypass (OPCAB) reduces operative morbidity without compromising mid-term clinical outcome.
OPCAB patients recover quicker and leave hospital sooner, benefiting both patients and health services. It has been suggested that recovery may be even faster if off-pump surgery is carried out through a left anterior thoracotomy (OPCAB-Th) instead of a median sternotomy (OPCAB-St). We propose to carry out a RCT comparing OPCAB-Th with OPCAB-St. The target population is all adults aged >16 years and <80 years considered for elective first time OPCAB. The primary outcome is the time from surgery until a participant is 'fit for discharge'; secondary outcomes include operative morbidity, inflammatory markers, intensive care stay, pain scores, patient-assessed outcome and use of hospital resources.
Inclusion criteria
- Patients aged >16 and <80 years undergoing elective, isolated first time coronary artery bypass grafting off-pump on the beating heart.
- Participating surgeon willing to carry out the operation via either surgical method.
Exclusion criteria
- Patients who have had previous cardiac surgery.
- Patients who have had previous lung surgery.
- Participating surgeon not willing to carry out the operation via either surgical method.
Principal investigators
- Angelini GD
- Reeves BC
- Rogers CA
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If you require any help, please contact: Dr Chris Rogers |
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